• Jul, 2021
  • 01-07-2021
  • New way to lower blood pressure: Strength training breathing muscles

    You suck at a straw that has resistance to sucking. The current regimen being used by researchers is 30 inhalations per day at high resistance.

    "IMST can be done in five minutes in your own home while you watch TV."

    The benefits were significant. Systolic bp dropped 9 points on average (exceeding benefits of 30 minutes walking 5 days a week), and equivalent also to some bp-lowing drug regimens. 6 weeks after the 36 older adults tested quit the training, most of the health benefits remained. (They' got funding to do another test with 100 people.)

    It's not yet known how it works: How strengthening breathing muscles ends up lowering blood pressure. A guess they have is that it causes cell lining blood vessels to provide more nitric oxide, causing them to relax.

    It also strengthens diaphragm muscles.

    IMST stands for High-Resistance Inspiratory Muscle Strength Training.
     

  • Jun, 2021
  • 27-06-2021
  • Biohackers aim at producing $7 insulin, compared with $300 insulin from Big Pharma

    Reportedly, insulin costs $1.50 to $5 per vial to make, but is sold for around $300. Biohackers are working on reverse engineering insulin to produce a recipe they will make public, and say they will sell vials for $7.

    Three large companies own 90% of the insulin in the world. Novo Nordisk, Lilly, and Sanofi. Millions of people need insulin, and some can't afford what they need.

    The FDA wants to open the market for insulin, according to some, and therefore they will approve the molecules created by the 'biohackers' [Open Insulin project]. Once they complete their work, they will make the recipe public so community labs around the world can produce it locally.

    'There was a time for being angry,' said one of the Open Insulin workers, 'It's not anger anymore. It's just determination.'


  • Jun, 2021
  • 14-06-2021
  • Pakistani town HIV outbreak among children

    As it it a poor, rural town where the parents work every day from the early morning, it is proving difficult to administer medicine to the young children in Rato Daro (in Sindh) who may require it for life.

    The outbreak is believed to stem from one doctor who was using unclean needles a couple of years ago. Although he was punished in the legal system, many say he was scapegoated and the responsibility lies with the government for providing good medical equipment.

     
  • Jun, 2021
  • 12-06-2021
  • FDA advisors are resigning because of Biogen's Alzheimer's drug approval

    The drug was approved, but when supporters were interviewed they couldn't say anything more compelling than that they were receiving the news positively because people suffered from Alzheimer's, without being able to say anything in favor of the drug itself.

    The drug came out a while back, and was not approved upon review last year (because no benefits were substantially proven, the FDA advisory board voted 10 against, 1 uncertain, 0 in favor), and since then nothing has changed, but the FDA decided to approve it now.

    It is rare for this type of decision to be overturned, and usually when it does happen, it's after a vote that is closer than the Biogen drug was.

    There are millions of potential consumers for the drug, and Biogen has priced it at $56,000 per year.

    Commenters said that after the third resignation, there might be some real attention on what's going on here.


    3 prestigious FDA advisors who quit:


     

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